Drug interactions
Fesoterodine + Scopolamine
Severity: Moderate
Fesoterodine and Scopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fesoterodine is an antimuscarinic for overactive bladder, so adding scopolamine duplicates anticholinergic effects. This raises the risk of dry mouth, constipation, urinary retention, blurred vision and cognitive impairment.
What this interaction means in plain words
Fesoterodine and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fesoterodine belongs to Genitourinary; Scopolamine belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Avoid duplicate antimuscarinic therapy where possible, and monitor for anticholinergic effects and cognition if both are required.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Scopolamine
Other interactions of Fesoterodine
Frequently asked questions
Can I take Fesoterodine with Scopolamine?
MediHelp rates the interaction as moderate. Fesoterodine and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fesoterodine is an antimuscarinic for overactive bladder, so adding scopolamine duplicates anticholinergic effects. This raises the risk of dry mouth, constipation, urinary retention, blurred vision and cognitive impairment.
How serious is the interaction between Fesoterodine and Scopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid duplicate antimuscarinic therapy where possible, and monitor for anticholinergic effects and cognition if both are required.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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