Drug interactions
Fexinidazole + Formoterol-mometasone
Severity: Major
Fexinidazole and Formoterol-mometasone: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fexinidazole is associated with QT prolongation and its labeling advises against co-use with other QT-prolonging drugs. Formoterol may add to QT effects and lower potassium, increasing the risk of torsades de pointes.
What this interaction means in plain words
Fexinidazole and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia contributing.
What to do
Avoid the combination where possible and use a non-QT-prolonging bronchodilator during fexinidazole therapy. If unavoidable, monitor ECG and correct electrolytes.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Fexinidazole with Formoterol-mometasone?
MediHelp rates the interaction as major. Fexinidazole and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fexinidazole is associated with QT prolongation and its labeling advises against co-use with other QT-prolonging drugs. Formoterol may add to QT effects and lower potassium, increasing the risk of torsades de pointes.
How serious is the interaction between Fexinidazole and Formoterol-mometasone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible and use a non-QT-prolonging bronchodilator during fexinidazole therapy. If unavoidable, monitor ECG and correct electrolytes.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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