Drug interactions
Fingolimod + Prednisolone
Severity: Moderate
Fingolimod and Prednisolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining prednisolone with fingolimod adds immunosuppression, which may increase the risk of infections. This is relevant when steroids are used for multiple sclerosis relapses in patients on fingolimod.
What this interaction means in plain words
Fingolimod and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Prednisolone belongs to Endocrine.
Why it happens
Additive immunosuppression from glucocorticoid effects and lymphocyte sequestration by fingolimod.
What to do
Monitor for signs of infection during and after combined therapy and keep steroid courses as short as possible. Screen and treat infections promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Prednisolone?
MediHelp rates the interaction as moderate. Fingolimod and Prednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining prednisolone with fingolimod adds immunosuppression, which may increase the risk of infections. This is relevant when steroids are used for multiple sclerosis relapses in patients on fingolimod.
How serious is the interaction between Fingolimod and Prednisolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection during and after combined therapy and keep steroid courses as short as possible. Screen and treat infections promptly.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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