Drug interactions
Fingolimod + Vincristine
Severity: Moderate
Fingolimod and Vincristine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vincristine is less myelosuppressive than other vinca alkaloids but is still part of immunosuppressive regimens. With fingolimod, infection risk may be modestly increased.
What this interaction means in plain words
Fingolimod and Vincristine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Vincristine belongs to Oncology.
Why it happens
Additive immunosuppression from cytotoxic therapy and fingolimod lymphocyte sequestration.
What to do
Monitor complete blood counts and for infection. Reassess the need for fingolimod during chemotherapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Other interactions of Vincristine
- Adenovirus types 4 and 7 live + Vincristine Contraindicated
- Apalutamide + Vincristine Major
- Atazanavir + Vincristine Major
- Ceritinib + Vincristine Major
- Chloramphenicol + Vincristine Major
- Clarithromycin + Vincristine Major
Frequently asked questions
Can I take Fingolimod with Vincristine?
MediHelp rates the interaction as moderate. Fingolimod and Vincristine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vincristine is less myelosuppressive than other vinca alkaloids but is still part of immunosuppressive regimens. With fingolimod, infection risk may be modestly increased.
How serious is the interaction between Fingolimod and Vincristine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and for infection. Reassess the need for fingolimod during chemotherapy.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Pimozide. The full list is on the Fingolimod page.
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