Drug interactions
Flavoxate + Henbane
Severity: Moderate
Flavoxate and Henbane: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine, which are antimuscarinic, and combining it with flavoxate increases anticholinergic effects. Confusion, tachycardia, urinary retention and dry mouth may occur.
What this interaction means in plain words
Flavoxate and Henbane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic receptor antagonism from plant tropane alkaloids.
What to do
Avoid concurrent use of henbane preparations with flavoxate where possible, and monitor for anticholinergic toxicity if used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Frequently asked questions
Can I take Flavoxate with Henbane?
MediHelp rates the interaction as moderate. Flavoxate and Henbane can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine, which are antimuscarinic, and combining it with flavoxate increases anticholinergic effects. Confusion, tachycardia, urinary retention and dry mouth may occur.
How serious is the interaction between Flavoxate and Henbane?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of henbane preparations with flavoxate where possible, and monitor for anticholinergic toxicity if used.
What other medicines interact with Flavoxate?
MediHelp also lists interactions of Flavoxate with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Flavoxate page.
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