Drug interactions
Flavoxate + Zotepine
Severity: Moderate
Flavoxate and Zotepine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Zotepine has antimuscarinic activity and can add to flavoxate's anticholinergic effects. Both drugs may also cause tachycardia, and zotepine lowers the seizure threshold.
What this interaction means in plain words
Flavoxate and Zotepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antimuscarinic effects.
What to do
Monitor for urinary retention, constipation, tachycardia and confusion. Reduce the flavoxate dose or stop it if anticholinergic effects emerge.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Frequently asked questions
Can I take Flavoxate with Zotepine?
MediHelp rates the interaction as moderate. Flavoxate and Zotepine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Zotepine has antimuscarinic activity and can add to flavoxate's anticholinergic effects. Both drugs may also cause tachycardia, and zotepine lowers the seizure threshold.
How serious is the interaction between Flavoxate and Zotepine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation, tachycardia and confusion. Reduce the flavoxate dose or stop it if anticholinergic effects emerge.
What other medicines interact with Flavoxate?
MediHelp also lists interactions of Flavoxate with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Flavoxate page.
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