Drug interactions
Flurbiprofen + Garlic
Severity: Minor
Flurbiprofen and Garlic: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have antiplatelet activity that may add to the platelet inhibition and GI bleeding risk of flurbiprofen. Evidence comes mainly from case reports and in vitro data.
What this interaction means in plain words
Flurbiprofen and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Garlic belongs to Gastrointestinal Tract.
Why it happens
Possible additive antiplatelet effect from garlic constituents with NSAID COX-1 inhibition.
What to do
Ask about garlic supplement use and advise patients to report unusual bruising or bleeding. Consider stopping high-dose garlic supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Flurbiprofen with Garlic?
MediHelp rates the interaction as minor. Flurbiprofen and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have antiplatelet activity that may add to the platelet inhibition and GI bleeding risk of flurbiprofen. Evidence comes mainly from case reports and in vitro data.
How serious is the interaction between Flurbiprofen and Garlic?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about garlic supplement use and advise patients to report unusual bruising or bleeding. Consider stopping high-dose garlic supplements before surgery.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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