Drug interactions
Flurbiprofen + Tafluprost
Severity: Minor
Flurbiprofen and Tafluprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic NSAIDs inhibit prostaglandin synthesis, and prostaglandin analogue eye drops lower intraocular pressure via the uveoscleral pathway. Reports of the effect on IOP are inconsistent, so the efficacy of tafluprost could be altered.
What this interaction means in plain words
Flurbiprofen and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Tafluprost belongs to Genitourinary.
Why it happens
Possible pharmacodynamic interference with prostaglandin-mediated effects on aqueous outflow; mechanism not firmly established.
What to do
Monitor intraocular pressure if an NSAID is started or stopped in a patient on tafluprost, and adjust glaucoma therapy if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Tafluprost
- Bimatoprost + Tafluprost Moderate
- Latanoprost + Tafluprost Moderate
- Tafluprost + Travoprost Moderate
- Acetylsalicylic acid + Tafluprost Minor
- Celecoxib + Tafluprost Minor
- Diclofenac + Tafluprost Minor
Frequently asked questions
Can I take Flurbiprofen with Tafluprost?
MediHelp rates the interaction as minor. Flurbiprofen and Tafluprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic NSAIDs inhibit prostaglandin synthesis, and prostaglandin analogue eye drops lower intraocular pressure via the uveoscleral pathway. Reports of the effect on IOP are inconsistent, so the efficacy of tafluprost could be altered.
How serious is the interaction between Flurbiprofen and Tafluprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor intraocular pressure if an NSAID is started or stopped in a patient on tafluprost, and adjust glaucoma therapy if control changes.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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