Drug interactions
Flurbiprofen + Valganciclovir
Severity: Minor
Flurbiprofen and Valganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Flurbiprofen may compete with ganciclovir for renal tubular secretion, which could raise ganciclovir exposure. NSAIDs can also reduce renal function, further impairing ganciclovir elimination and increasing the risk of myelosuppression.
What this interaction means in plain words
Flurbiprofen and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Valganciclovir belongs to Anti Virals.
Why it happens
Competition for renal tubular anionic secretion plus NSAID-related reduction in renal perfusion may decrease ganciclovir clearance.
What to do
Monitor renal function and blood counts during combined use, and adjust valganciclovir dosing to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Valganciclovir
Frequently asked questions
Can I take Flurbiprofen with Valganciclovir?
MediHelp rates the interaction as minor. Flurbiprofen and Valganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Flurbiprofen may compete with ganciclovir for renal tubular secretion, which could raise ganciclovir exposure. NSAIDs can also reduce renal function, further impairing ganciclovir elimination and increasing the risk of myelosuppression.
How serious is the interaction between Flurbiprofen and Valganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and blood counts during combined use, and adjust valganciclovir dosing to creatinine clearance.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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