Drug interactions
Fluticasone furoate + Quinidine
Severity: Minor
Fluticasone furoate and Quinidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinidine is a CYP3A4 substrate with weak inhibitory effect on this enzyme, so a clinically important rise in fluticasone furoate is unlikely. Any effect would be minor.
What this interaction means in plain words
Fluticasone furoate and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak CYP3A4 inhibition by quinidine; not well established for this pair.
What to do
No routine action is needed. Be aware of systemic corticosteroid effects with chronic use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Frequently asked questions
Can I take Fluticasone furoate with Quinidine?
MediHelp rates the interaction as minor. Fluticasone furoate and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinidine is a CYP3A4 substrate with weak inhibitory effect on this enzyme, so a clinically important rise in fluticasone furoate is unlikely. Any effect would be minor.
How serious is the interaction between Fluticasone furoate and Quinidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Be aware of systemic corticosteroid effects with chronic use.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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