Drug interactions
Fluticasone-vilanterol + Olanzapine
Severity: Minor
Fluticasone-vilanterol and Olanzapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Olanzapine has a small effect on the QT interval and can cause tachycardia, and vilanterol adds adrenergic cardiac stimulation. The clinical risk is generally low at usual doses.
What this interaction means in plain words
Fluticasone-vilanterol and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluticasone-vilanterol belongs to Respiratory; Olanzapine belongs to Central Nervous System.
Why it happens
Possible additive cardiac effects on heart rate and repolarization.
What to do
Usually no action beyond monitoring for palpitations; check ECG and electrolytes if additional QT risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluticasone-vilanterol
Other interactions of Olanzapine
Frequently asked questions
Can I take Fluticasone-vilanterol with Olanzapine?
MediHelp rates the interaction as minor. Fluticasone-vilanterol and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Olanzapine has a small effect on the QT interval and can cause tachycardia, and vilanterol adds adrenergic cardiac stimulation. The clinical risk is generally low at usual doses.
How serious is the interaction between Fluticasone-vilanterol and Olanzapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Usually no action beyond monitoring for palpitations; check ECG and electrolytes if additional QT risk factors are present.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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