Drug interactions
Formoterol + Levofloxacin
Severity: Moderate
Formoterol and Levofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levofloxacin can prolong the QT interval, and formoterol can contribute to QTc effects, tachycardia and hypokalemia. The combination may increase the risk of ventricular arrhythmia, particularly in older patients or those with cardiac disease.
What this interaction means in plain words
Formoterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Levofloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia.
What to do
Correct potassium and magnesium and consider an ECG in patients with cardiac risk factors; choose a non-QT-prolonging antibiotic where practical.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Frequently asked questions
Can I take Formoterol with Levofloxacin?
MediHelp rates the interaction as moderate. Formoterol and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Levofloxacin can prolong the QT interval, and formoterol can contribute to QTc effects, tachycardia and hypokalemia. The combination may increase the risk of ventricular arrhythmia, particularly in older patients or those with cardiac disease.
How serious is the interaction between Formoterol and Levofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium and consider an ECG in patients with cardiac risk factors; choose a non-QT-prolonging antibiotic where practical.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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