Drug interactions
Formoterol + Nebivolol
Severity: Moderate
Formoterol and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nebivolol is a beta-1 selective blocker that may reduce the bronchodilator effect of formoterol and, at higher doses or in susceptible patients, provoke bronchospasm. The risk is mainly in asthma or COPD.
What this interaction means in plain words
Formoterol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Nebivolol belongs to Cardiovascular.
Why it happens
Pharmacodynamic antagonism at beta-adrenergic receptors, with selectivity lost at higher nebivolol doses.
What to do
Use the lowest effective nebivolol dose and monitor respiratory symptoms and peak flow. Switch therapy if bronchospasm or reduced bronchodilator response occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Formoterol with Nebivolol?
MediHelp rates the interaction as moderate. Formoterol and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nebivolol is a beta-1 selective blocker that may reduce the bronchodilator effect of formoterol and, at higher doses or in susceptible patients, provoke bronchospasm. The risk is mainly in asthma or COPD.
How serious is the interaction between Formoterol and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective nebivolol dose and monitor respiratory symptoms and peak flow. Switch therapy if bronchospasm or reduced bronchodilator response occurs.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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