Drug interactions
Formoterol-mometasone + Lofepramine
Severity: Moderate
Formoterol-mometasone and Lofepramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lofepramine is a tricyclic antidepressant that can have cardiac effects and potentiate adrenergic responses. With formoterol it may increase tachycardia and arrhythmia risk, especially in patients with heart disease.
What this interaction means in plain words
Formoterol-mometasone and Lofepramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive cardiac and QT effects, plus tricyclic inhibition of norepinephrine reuptake that may amplify beta-agonist effects.
What to do
Monitor heart rate, symptoms and ECG, particularly in patients with cardiac disease. Consider another antidepressant if arrhythmias or marked tachycardia occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Lofepramine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Formoterol-mometasone with Lofepramine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Lofepramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lofepramine is a tricyclic antidepressant that can have cardiac effects and potentiate adrenergic responses. With formoterol it may increase tachycardia and arrhythmia risk, especially in patients with heart disease.
How serious is the interaction between Formoterol-mometasone and Lofepramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, symptoms and ECG, particularly in patients with cardiac disease. Consider another antidepressant if arrhythmias or marked tachycardia occur.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
