Drug interactions
Formoterol-mometasone + Loxapine inhaled
Severity: Major
Formoterol-mometasone and Loxapine inhaled: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled loxapine can cause bronchospasm in patients with airway disease. Patients using formoterol and mometasone usually have asthma or COPD, so the underlying condition is the main concern rather than a direct drug-drug effect.
What this interaction means in plain words
Formoterol-mometasone and Loxapine inhaled can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Inhaled loxapine can provoke bronchospasm in reactive airways; this is a shared-risk situation rather than a defined pharmacokinetic interaction.
What to do
Inhaled loxapine is restricted to patients without active airway disease, so choose an alternative route or agent for agitation in patients on these inhalers. If it must be given, have a short-acting bronchodilator available and monitor for wheeze.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Formoterol-mometasone with Loxapine inhaled?
MediHelp rates the interaction as major. Formoterol-mometasone and Loxapine inhaled can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Inhaled loxapine can cause bronchospasm in patients with airway disease. Patients using formoterol and mometasone usually have asthma or COPD, so the underlying condition is the main concern rather than a direct drug-drug effect.
How serious is the interaction between Formoterol-mometasone and Loxapine inhaled?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Inhaled loxapine is restricted to patients without active airway disease, so choose an alternative route or agent for agitation in patients on these inhalers. If it must be given, have a short-acting bronchodilator available and monitor for wheeze.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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