Drug interactions
Formoterol-mometasone + Lumefantrine
Severity: Major
Formoterol-mometasone and Lumefantrine: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lumefantrine can prolong the QT interval. Formoterol may add to this effect and lower potassium, increasing the risk of arrhythmia.
What this interaction means in plain words
Formoterol-mometasone and Lumefantrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia contributing.
What to do
Check baseline ECG and correct potassium and magnesium. Monitor ECG during treatment, and prefer a bronchodilator with less QT effect if feasible.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Formoterol-mometasone with Lumefantrine?
MediHelp rates the interaction as major. Formoterol-mometasone and Lumefantrine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lumefantrine can prolong the QT interval. Formoterol may add to this effect and lower potassium, increasing the risk of arrhythmia.
How serious is the interaction between Formoterol-mometasone and Lumefantrine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and correct potassium and magnesium. Monitor ECG during treatment, and prefer a bronchodilator with less QT effect if feasible.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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