Drug interactions
Formoterol-mometasone + Pindolol
Severity: Major
Formoterol-mometasone and Pindolol: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol is a non-selective beta-blocker that can antagonize formoterol's bronchodilation and trigger bronchospasm in patients with asthma or COPD. Its partial agonist activity does not reliably prevent this.
What this interaction means in plain words
Formoterol-mometasone and Pindolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Competitive beta-adrenoceptor blockade opposes beta-2 agonist effects.
What to do
Avoid pindolol in patients with asthma; if a beta-blocker is needed in COPD, prefer a cardioselective agent and monitor respiratory function.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Formoterol-mometasone and Pindolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Formoterol-mometasone with Pindolol?
MediHelp rates the interaction as major. Formoterol-mometasone and Pindolol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pindolol is a non-selective beta-blocker that can antagonize formoterol's bronchodilation and trigger bronchospasm in patients with asthma or COPD. Its partial agonist activity does not reliably prevent this.
How serious is the interaction between Formoterol-mometasone and Pindolol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid pindolol in patients with asthma; if a beta-blocker is needed in COPD, prefer a cardioselective agent and monitor respiratory function.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
