Drug interactions
Formoterol-mometasone + Pirbuterol
Severity: Moderate
Formoterol-mometasone and Pirbuterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pirbuterol is a short-acting beta-2 agonist and formoterol is a long-acting one. Concurrent use can cause additive tachycardia, tremor, hypokalemia and arrhythmia, though short-acting rescue use alongside a maintenance LABA is common.
What this interaction means in plain words
Formoterol-mometasone and Pirbuterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-2 adrenergic agonism, including beta-mediated potassium shift.
What to do
Limit pirbuterol to as-needed rescue use, and monitor heart rate and potassium if frequent use is required; frequent rescue use signals poor control needing reassessment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Formoterol-mometasone with Pirbuterol?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Pirbuterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pirbuterol is a short-acting beta-2 agonist and formoterol is a long-acting one. Concurrent use can cause additive tachycardia, tremor, hypokalemia and arrhythmia, though short-acting rescue use alongside a maintenance LABA is common.
How serious is the interaction between Formoterol-mometasone and Pirbuterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit pirbuterol to as-needed rescue use, and monitor heart rate and potassium if frequent use is required; frequent rescue use signals poor control needing reassessment.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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