Drug interactions
Formoterol-mometasone + Venlafaxine
Severity: Moderate
Formoterol-mometasone and Venlafaxine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both formoterol and venlafaxine can prolong the QTc interval, and beta2-agonists may also cause hypokalemia and tachycardia. Combined use may add to the risk of ventricular arrhythmia, especially with high doses or other risk factors.
What this interaction means in plain words
Formoterol-mometasone and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Venlafaxine belongs to Central Nervous System.
Why it happens
Additive QT prolongation, with beta2-agonist-induced hypokalemia and sympathetic stimulation increasing arrhythmia susceptibility.
What to do
Use the lowest effective doses and correct potassium and magnesium abnormalities. Obtain an ECG in patients with cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Venlafaxine
- Isocarboxazid + Venlafaxine Contraindicated
- Methylene blue + Venlafaxine Contraindicated
- Phenelzine + Venlafaxine Contraindicated
- Procarbazine + Venlafaxine Contraindicated
- Rasagiline + Venlafaxine Contraindicated
- Safinamide + Venlafaxine Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Venlafaxine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Venlafaxine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both formoterol and venlafaxine can prolong the QTc interval, and beta2-agonists may also cause hypokalemia and tachycardia. Combined use may add to the risk of ventricular arrhythmia, especially with high doses or other risk factors.
How serious is the interaction between Formoterol-mometasone and Venlafaxine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and correct potassium and magnesium abnormalities. Obtain an ECG in patients with cardiac disease or other QT-prolonging drugs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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