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Drug interactions

Formoterol-mometasone + Yohimbine

Severity: Moderate

Formoterol-mometasone and Yohimbine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Yohimbine is an alpha-2 antagonist that increases noradrenergic outflow, raising blood pressure and heart rate. With formoterol, these sympathetic effects may be additive and cause tachycardia, anxiety or hypertension.

What this interaction means in plain words

Formoterol-mometasone and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive adrenergic stimulation.

What to do

Monitor blood pressure and heart rate. Avoid in patients with significant cardiovascular disease.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Formoterol-mometasone with Yohimbine?

MediHelp rates the interaction as moderate. Formoterol-mometasone and Yohimbine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Yohimbine is an alpha-2 antagonist that increases noradrenergic outflow, raising blood pressure and heart rate. With formoterol, these sympathetic effects may be additive and cause tachycardia, anxiety or hypertension.

How serious is the interaction between Formoterol-mometasone and Yohimbine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate. Avoid in patients with significant cardiovascular disease.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

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