Drug interactions
Forskolin + Indomethacin
Severity: Minor
Forskolin and Indomethacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin has been reported to inhibit platelet aggregation in experimental settings, and indomethacin also impairs platelet function. The combination may theoretically increase bleeding tendency.
What this interaction means in plain words
Forskolin and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive antiplatelet effect; forskolin raises cyclic AMP in platelets while indomethacin inhibits cyclooxygenase.
What to do
Be aware of the potential for bleeding and ask patients to report unusual bruising or bleeding. Avoid forskolin supplements in patients with bleeding risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Forskolin with Indomethacin?
MediHelp rates the interaction as minor. Forskolin and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin has been reported to inhibit platelet aggregation in experimental settings, and indomethacin also impairs platelet function. The combination may theoretically increase bleeding tendency.
How serious is the interaction between Forskolin and Indomethacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware of the potential for bleeding and ask patients to report unusual bruising or bleeding. Avoid forskolin supplements in patients with bleeding risk factors.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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