Drug interactions
Forskolin + Sulindac
Severity: Minor
Forskolin and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin has been reported to inhibit platelet aggregation in experimental settings. With sulindac, which also impairs platelet function, there is a theoretical increase in bleeding tendency.
What this interaction means in plain words
Forskolin and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive antiplatelet effect via forskolin-induced cyclic AMP elevation and NSAID cyclooxygenase inhibition.
What to do
Counsel patients to report unusual bruising or bleeding. Avoid the combination in patients with other bleeding risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Frequently asked questions
Can I take Forskolin with Sulindac?
MediHelp rates the interaction as minor. Forskolin and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin has been reported to inhibit platelet aggregation in experimental settings. With sulindac, which also impairs platelet function, there is a theoretical increase in bleeding tendency.
How serious is the interaction between Forskolin and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report unusual bruising or bleeding. Avoid the combination in patients with other bleeding risk factors.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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