Drug interactions
Foscarnet + Telavancin
Severity: Major
Foscarnet and Telavancin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Foscarnet can prolong the QT interval and cause electrolyte disturbances such as hypocalcemia, hypomagnesemia and hypokalemia, and telavancin may add to the QT effect. Both drugs are also nephrotoxic, further raising risk.
What this interaction means in plain words
Foscarnet and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Foscarnet belongs to Anti Virals; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, compounded by foscarnet-induced electrolyte disturbances and additive nephrotoxicity.
What to do
Monitor ECG, serum calcium, magnesium, potassium and renal function throughout co-therapy, and correct deficits promptly. Use an alternative agent where feasible.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Foscarnet with Telavancin?
MediHelp rates the interaction as major. Foscarnet and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Foscarnet can prolong the QT interval and cause electrolyte disturbances such as hypocalcemia, hypomagnesemia and hypokalemia, and telavancin may add to the QT effect. Both drugs are also nephrotoxic, further raising risk.
How serious is the interaction between Foscarnet and Telavancin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, serum calcium, magnesium, potassium and renal function throughout co-therapy, and correct deficits promptly. Use an alternative agent where feasible.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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