Drug interactions
Foscarnet + Tiludronate
Severity: Moderate
Foscarnet and Tiludronate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum calcium: tiludronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may increase the risk of symptomatic hypocalcemia.
What this interaction means in plain words
Foscarnet and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Foscarnet belongs to Anti Virals; Tiludronate belongs to Musculoskeletal.
Why it happens
Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.
What to do
Monitor calcium, magnesium and ionized calcium during foscarnet therapy and replace deficits promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiludronate
- Acetylsalicylic acid + Tiludronate Moderate
- Aluminum hydroxide + Tiludronate Moderate
- Calcium acetate + Tiludronate Moderate
- Calcium carbonate + Tiludronate Moderate
- Calcium chloride + Tiludronate Moderate
- Calcium citrate + Tiludronate Moderate
Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Foscarnet with Tiludronate?
MediHelp rates the interaction as moderate. Foscarnet and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum calcium: tiludronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may increase the risk of symptomatic hypocalcemia.
How serious is the interaction between Foscarnet and Tiludronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor calcium, magnesium and ionized calcium during foscarnet therapy and replace deficits promptly.
What other medicines interact with Tiludronate?
MediHelp also lists interactions of Tiludronate with, for example, Acetylsalicylic acid, Aluminum hydroxide, Calcium acetate. The full list is on the Tiludronate page.
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