Drug interactions
Fosinopril-hydrochlorothiazide + Insulin detemir
Severity: Minor
Fosinopril-hydrochlorothiazide and Insulin detemir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors can improve insulin sensitivity and occasionally cause hypoglycemia in insulin-treated patients. Hydrochlorothiazide may counter this by worsening glycemic control.
What this interaction means in plain words
Fosinopril-hydrochlorothiazide and Insulin detemir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fosinopril-hydrochlorothiazide belongs to Cardiovascular; Insulin detemir belongs to Endocrine.
Why it happens
ACE inhibitors may enhance insulin sensitivity, whereas thiazides can impair glucose tolerance.
What to do
Monitor blood glucose after starting or changing therapy and adjust the insulin dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Other interactions of Insulin detemir
Frequently asked questions
Can I take Fosinopril-hydrochlorothiazide with Insulin detemir?
MediHelp rates the interaction as minor. Fosinopril-hydrochlorothiazide and Insulin detemir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors can improve insulin sensitivity and occasionally cause hypoglycemia in insulin-treated patients. Hydrochlorothiazide may counter this by worsening glycemic control.
How serious is the interaction between Fosinopril-hydrochlorothiazide and Insulin detemir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or changing therapy and adjust the insulin dose if needed.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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