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Drug interactions

Fosinopril-hydrochlorothiazide + Juniper

Severity: Minor

Fosinopril-hydrochlorothiazide and Juniper: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Juniper has diuretic properties and could add to the effects of hydrochlorothiazide, with possible fluid and electrolyte loss. At large doses it may also be nephrotoxic, which is a concern with an ACE inhibitor and diuretic combination.

What this interaction means in plain words

Fosinopril-hydrochlorothiazide and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive diuretic effect; the interaction is not well characterized.

What to do

Advise patients to avoid high-dose juniper products. Monitor electrolytes, blood pressure and renal function if used regularly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fosinopril-hydrochlorothiazide with Juniper?

MediHelp rates the interaction as minor. Fosinopril-hydrochlorothiazide and Juniper have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Juniper has diuretic properties and could add to the effects of hydrochlorothiazide, with possible fluid and electrolyte loss. At large doses it may also be nephrotoxic, which is a concern with an ACE inhibitor and diuretic combination.

How serious is the interaction between Fosinopril-hydrochlorothiazide and Juniper?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid high-dose juniper products. Monitor electrolytes, blood pressure and renal function if used regularly.

What other medicines interact with Fosinopril-hydrochlorothiazide?

MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.

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