Drug interactions
Fosinopril-hydrochlorothiazide + Penicillin g aqueous
Severity: Minor
Fosinopril-hydrochlorothiazide and Penicillin g aqueous: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are secreted by renal tubules, and competition may raise levels of either. The effect is usually small, although high-dose penicillin G also carries a potassium or sodium load.
What this interaction means in plain words
Fosinopril-hydrochlorothiazide and Penicillin g aqueous have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Competition for renal tubular secretion via organic anion transporters.
What to do
No routine adjustment; monitor renal function and electrolytes during high-dose penicillin G therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Fosinopril-hydrochlorothiazide with Penicillin g aqueous?
MediHelp rates the interaction as minor. Fosinopril-hydrochlorothiazide and Penicillin g aqueous have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are secreted by renal tubules, and competition may raise levels of either. The effect is usually small, although high-dose penicillin G also carries a potassium or sodium load.
How serious is the interaction between Fosinopril-hydrochlorothiazide and Penicillin g aqueous?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment; monitor renal function and electrolytes during high-dose penicillin G therapy.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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