Drug interactions
Fosinopril-hydrochlorothiazide + Pindolol
Severity: Minor
Fosinopril-hydrochlorothiazide and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol adds to the blood pressure lowering of fosinopril and hydrochlorothiazide, which may be useful but can cause excessive hypotension or bradycardia. Thiazides may impair glucose tolerance, and beta-blockers can mask hypoglycemia.
What this interaction means in plain words
Fosinopril-hydrochlorothiazide and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive pharmacodynamic effects.
What to do
Monitor blood pressure, heart rate and serum potassium when starting or adjusting doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Fosinopril-hydrochlorothiazide with Pindolol?
MediHelp rates the interaction as minor. Fosinopril-hydrochlorothiazide and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pindolol adds to the blood pressure lowering of fosinopril and hydrochlorothiazide, which may be useful but can cause excessive hypotension or bradycardia. Thiazides may impair glucose tolerance, and beta-blockers can mask hypoglycemia.
How serious is the interaction between Fosinopril-hydrochlorothiazide and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium when starting or adjusting doses.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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