Drug interactions
Fosinopril-hydrochlorothiazide + Triamcinolone acetonide injectable
Severity: Minor
Fosinopril-hydrochlorothiazide and Triamcinolone acetonide injectable: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids can promote potassium loss and fluid retention, which adds to the potassium wasting of hydrochlorothiazide and may blunt blood pressure control. Triamcinolone has little mineralocorticoid activity, so the effect is smaller than with other steroids.
What this interaction means in plain words
Fosinopril-hydrochlorothiazide and Triamcinolone acetonide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive renal potassium loss and sodium retention with corticosteroid exposure.
What to do
Check serum potassium and blood pressure if repeated or high-dose triamcinolone is given, and replace potassium as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fosinopril-hydrochlorothiazide
- Aliskiren + Fosinopril-hydrochlorothiazide Contraindicated
- Dofetilide + Fosinopril-hydrochlorothiazide Contraindicated
- Fosinopril-hydrochlorothiazide + Protein a column Contraindicated
- Fosinopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aldesleukin + Fosinopril-hydrochlorothiazide Major
- Amifostine + Fosinopril-hydrochlorothiazide Major
Frequently asked questions
Can I take Fosinopril-hydrochlorothiazide with Triamcinolone acetonide injectable?
MediHelp rates the interaction as minor. Fosinopril-hydrochlorothiazide and Triamcinolone acetonide injectable have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids can promote potassium loss and fluid retention, which adds to the potassium wasting of hydrochlorothiazide and may blunt blood pressure control. Triamcinolone has little mineralocorticoid activity, so the effect is smaller than with other steroids.
How serious is the interaction between Fosinopril-hydrochlorothiazide and Triamcinolone acetonide injectable?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and blood pressure if repeated or high-dose triamcinolone is given, and replace potassium as needed.
What other medicines interact with Fosinopril-hydrochlorothiazide?
MediHelp also lists interactions of Fosinopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Fosinopril-hydrochlorothiazide page.
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