Drug interactions
Ganciclovir + Pivmecillinam
Severity: Minor
Ganciclovir and Pivmecillinam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are eliminated by the kidneys, partly through active tubular secretion. Competition could modestly raise concentrations of either drug. Clinically significant effects are not well documented.
What this interaction means in plain words
Ganciclovir and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ganciclovir belongs to Anti Virals; Pivmecillinam belongs to Anti Bacterial.
Why it happens
Possible competition for renal tubular secretion via organic anion transporters.
What to do
No routine change is needed; monitor renal function and for ganciclovir hematologic toxicity in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ganciclovir
Other interactions of Pivmecillinam
- Doxycycline + Pivmecillinam Moderate
- Minocycline + Pivmecillinam Moderate
- Pivmecillinam + Probenecid Moderate
- Pivmecillinam + Tetracycline Moderate
- Acetylsalicylic acid + Pivmecillinam Minor
- Acyclovir + Pivmecillinam Minor
Frequently asked questions
Can I take Ganciclovir with Pivmecillinam?
MediHelp rates the interaction as minor. Ganciclovir and Pivmecillinam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are eliminated by the kidneys, partly through active tubular secretion. Competition could modestly raise concentrations of either drug. Clinically significant effects are not well documented.
How serious is the interaction between Ganciclovir and Pivmecillinam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor renal function and for ganciclovir hematologic toxicity in patients with renal impairment.
What other medicines interact with Ganciclovir?
MediHelp also lists interactions of Ganciclovir with, for example, Bacitracin, Cilastatin-imipenem, Didanosine. The full list is on the Ganciclovir page.
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