Drug interactions
Garlic + Tolmetin
Severity: Minor
Garlic and Tolmetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements may have mild antiplatelet activity and could add to the bleeding risk of an NSAID. The evidence is limited and mostly theoretical.
What this interaction means in plain words
Garlic and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Garlic belongs to Gastrointestinal Tract; Tolmetin belongs to Musculoskeletal.
Why it happens
Garlic constituents may inhibit platelet aggregation, adding to NSAID COX-1 inhibition.
What to do
Counsel patients to report unusual bruising or bleeding and consider stopping high-dose garlic supplements while taking tolmetin.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Garlic with Tolmetin?
MediHelp rates the interaction as minor. Garlic and Tolmetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements may have mild antiplatelet activity and could add to the bleeding risk of an NSAID. The evidence is limited and mostly theoretical.
How serious is the interaction between Garlic and Tolmetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report unusual bruising or bleeding and consider stopping high-dose garlic supplements while taking tolmetin.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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