Drug interactions
Ginger + Indomethacin
Severity: Minor
Ginger and Indomethacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger supplements may have mild antiplatelet activity that could theoretically add to indomethacin bleeding risk. Clinical evidence is weak.
What this interaction means in plain words
Ginger and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ginger belongs to Gastrointestinal Tract; Indomethacin belongs to Musculoskeletal.
Why it happens
Ginger constituents may inhibit thromboxane synthesis and platelet aggregation, additive with NSAID effects.
What to do
Advise patients to report unusual bruising or bleeding when taking ginger supplements with indomethacin. Avoid high-dose supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Ginger with Indomethacin?
MediHelp rates the interaction as minor. Ginger and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger supplements may have mild antiplatelet activity that could theoretically add to indomethacin bleeding risk. Clinical evidence is weak.
How serious is the interaction between Ginger and Indomethacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report unusual bruising or bleeding when taking ginger supplements with indomethacin. Avoid high-dose supplements before surgery.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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