Drug interactions
Ginger + Ketoprofen
Severity: Minor
Ginger and Ketoprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger may have mild antiplatelet activity, which could add to the platelet inhibition and gastrointestinal bleeding risk of ketoprofen. Clinical evidence of meaningful harm is limited.
What this interaction means in plain words
Ginger and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ginger belongs to Gastrointestinal Tract; Ketoprofen belongs to Musculoskeletal.
Why it happens
Additive antiplatelet effects, with ginger possibly inhibiting thromboxane synthesis, combined with NSAID cyclooxygenase inhibition.
What to do
Counsel patients to report bruising, black stools or other bleeding, and avoid high-dose ginger supplements during regular ketoprofen use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketoprofen
- Ketoprofen + Ketorolac Contraindicated
- Ketoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Ketoprofen Major
- Acemetacin + Ketoprofen Major
- Acetylsalicylic acid + Ketoprofen Major
- Alteplase + Ketoprofen Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Ginger with Ketoprofen?
MediHelp rates the interaction as minor. Ginger and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger may have mild antiplatelet activity, which could add to the platelet inhibition and gastrointestinal bleeding risk of ketoprofen. Clinical evidence of meaningful harm is limited.
How serious is the interaction between Ginger and Ketoprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to report bruising, black stools or other bleeding, and avoid high-dose ginger supplements during regular ketoprofen use.
What other medicines interact with Ketoprofen?
MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.
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