Drug interactions
Ginger + Sulindac
Severity: Minor
Ginger and Sulindac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginger has shown antiplatelet activity in laboratory studies and might add to NSAID-related bleeding risk. Clinical evidence of meaningful interaction is weak.
What this interaction means in plain words
Ginger and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ginger belongs to Gastrointestinal Tract; Sulindac belongs to Musculoskeletal.
Why it happens
Ginger constituents may inhibit thromboxane synthesis and platelet aggregation, theoretically additive to NSAIDs.
What to do
Counsel patients to avoid large supplemental doses of ginger and report bruising or bleeding. No routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sulindac
- Ketorolac intranasal + Sulindac Contraindicated
- Ketorolac + Sulindac Contraindicated
- Aceclofenac + Sulindac Major
- Acetylsalicylic acid + Sulindac Major
- Alteplase + Sulindac Major
- Amiloride + Sulindac Major
Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Frequently asked questions
Can I take Ginger with Sulindac?
MediHelp rates the interaction as minor. Ginger and Sulindac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ginger has shown antiplatelet activity in laboratory studies and might add to NSAID-related bleeding risk. Clinical evidence of meaningful interaction is weak.
How serious is the interaction between Ginger and Sulindac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid large supplemental doses of ginger and report bruising or bleeding. No routine dose change is needed.
What other medicines interact with Sulindac?
MediHelp also lists interactions of Sulindac with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Sulindac page.
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