Drug interactions
Ginko biloba + Prasugrel
Severity: Moderate
Ginko biloba and Prasugrel: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prasugrel is a potent P2Y12 platelet inhibitor with a substantial bleeding risk, and ginkgo may have mild antiplatelet effects. Clinical evidence of a real effect is conflicting, but the additive risk is plausible.
What this interaction means in plain words
Ginko biloba and Prasugrel can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ginko biloba belongs to Gastrointestinal Tract; Prasugrel belongs to Cardiovascular.
Why it happens
Additive platelet inhibition through irreversible P2Y12 blockade plus ginkgolide antagonism of platelet-activating factor.
What to do
Advise patients to avoid ginkgo while taking prasugrel. Monitor for bleeding if it is continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Prasugrel
Frequently asked questions
Can I take Ginko biloba with Prasugrel?
MediHelp rates the interaction as moderate. Ginko biloba and Prasugrel can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prasugrel is a potent P2Y12 platelet inhibitor with a substantial bleeding risk, and ginkgo may have mild antiplatelet effects. Clinical evidence of a real effect is conflicting, but the additive risk is plausible.
How serious is the interaction between Ginko biloba and Prasugrel?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid ginkgo while taking prasugrel. Monitor for bleeding if it is continued.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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