Drug interactions
Glimepiride + Shark cartilage
Severity: Minor
Glimepiride and Shark cartilage: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Shark cartilage supplements have been suggested to lower blood glucose, which could add to glimepiride's effect. The interaction is theoretical and data are very limited.
What this interaction means in plain words
Glimepiride and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive hypoglycemic effect; mechanism not established.
What to do
Advise patients to monitor blood glucose if taking shark cartilage and report symptoms of hypoglycemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Glimepiride
Frequently asked questions
Can I take Glimepiride with Shark cartilage?
MediHelp rates the interaction as minor. Glimepiride and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage supplements have been suggested to lower blood glucose, which could add to glimepiride's effect. The interaction is theoretical and data are very limited.
How serious is the interaction between Glimepiride and Shark cartilage?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to monitor blood glucose if taking shark cartilage and report symptoms of hypoglycemia.
What other medicines interact with Glimepiride?
MediHelp also lists interactions of Glimepiride with, for example, Fluconazole, Insulin degludec-liraglutide, Insulin glargine-lixisenatide. The full list is on the Glimepiride page.
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