Drug interactions
Glucagon intranasal + Nebivolol
Severity: Minor
Glucagon intranasal and Nebivolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon can stimulate catecholamine release, which in a patient on a beta-blocker may cause a transient rise in blood pressure and heart rate. The effect is usually short-lived.
What this interaction means in plain words
Glucagon intranasal and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucagon-induced catecholamine release with beta-blockade leaving alpha-mediated pressor effects unopposed.
What to do
Monitor pulse and blood pressure after glucagon administration in patients taking nebivolol. Confirm blood glucose recovery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Frequently asked questions
Can I take Glucagon intranasal with Nebivolol?
MediHelp rates the interaction as minor. Glucagon intranasal and Nebivolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon can stimulate catecholamine release, which in a patient on a beta-blocker may cause a transient rise in blood pressure and heart rate. The effect is usually short-lived.
How serious is the interaction between Glucagon intranasal and Nebivolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor pulse and blood pressure after glucagon administration in patients taking nebivolol. Confirm blood glucose recovery.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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