Drug interactions
Glucagon intranasal + Umeclidinium-vilanterol
Severity: Minor
Glucagon intranasal and Umeclidinium-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon inhibits gastrointestinal motility, and anticholinergics add to this effect, though systemic exposure to inhaled umeclidinium is low. The interaction is mainly relevant when glucagon is used for diagnostic purposes, and any added effect on bowel motility is likely small.
What this interaction means in plain words
Glucagon intranasal and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive suppression of gastrointestinal motility from glucagon and antimuscarinic activity.
What to do
No routine action is needed for emergency glucagon use for hypoglycemia. Watch for constipation or abdominal symptoms if both are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium-vilanterol
Frequently asked questions
Can I take Glucagon intranasal with Umeclidinium-vilanterol?
MediHelp rates the interaction as minor. Glucagon intranasal and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon inhibits gastrointestinal motility, and anticholinergics add to this effect, though systemic exposure to inhaled umeclidinium is low. The interaction is mainly relevant when glucagon is used for diagnostic purposes, and any added effect on bowel motility is likely small.
How serious is the interaction between Glucagon intranasal and Umeclidinium-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed for emergency glucagon use for hypoglycemia. Watch for constipation or abdominal symptoms if both are used regularly.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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