Drug interactions
Glyburide + Pitavastatin
Severity: Minor
Glyburide and Pitavastatin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glyburide may weakly inhibit hepatic uptake of pitavastatin, but no clinically important effect has been established.
What this interaction means in plain words
Glyburide and Pitavastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Glyburide belongs to Endocrine; Pitavastatin belongs to Cardiovascular.
Why it happens
Possible OATP1B1 inhibition by glyburide.
What to do
No dose adjustment is needed. Counsel patients to report muscle pain.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Pitavastatin
- Cyclosporine + Pitavastatin Contraindicated
- Cyclosporin + Pitavastatin Contraindicated
- Erythromycin base + Pitavastatin Major
- Erythromycin ethylsuccinate + Pitavastatin Major
- Erythromycin lactobionate + Pitavastatin Major
- Erythromycin stearate + Pitavastatin Major
Other interactions of Glyburide
- Bosentan + Glyburide Contraindicated
- Cholic acid + Glyburide Major
- Ciprofloxacin + Glyburide Major
- Clarithromycin + Glyburide Major
- Fluconazole + Glyburide Major
- Glyburide + Insulin degludec-liraglutide Major
Frequently asked questions
Can I take Glyburide with Pitavastatin?
MediHelp rates the interaction as minor. Glyburide and Pitavastatin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glyburide may weakly inhibit hepatic uptake of pitavastatin, but no clinically important effect has been established.
How serious is the interaction between Glyburide and Pitavastatin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Counsel patients to report muscle pain.
What other medicines interact with Pitavastatin?
MediHelp also lists interactions of Pitavastatin with, for example, Cyclosporine, Cyclosporin, Erythromycin base. The full list is on the Pitavastatin page.
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