Drug interactions
Glyburide + Tongkat ali
Severity: Minor
Glyburide and Tongkat ali: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tongkat ali has been reported to have glucose-lowering effects in preclinical and limited human data. Combined with glyburide it could contribute to hypoglycemia.
What this interaction means in plain words
Glyburide and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; mechanism is not well established.
What to do
Ask patients about herbal supplement use and monitor blood glucose. Adjust the glyburide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Glyburide and Tongkat ali, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Glyburide
- Bosentan + Glyburide Contraindicated
- Cholic acid + Glyburide Major
- Ciprofloxacin + Glyburide Major
- Clarithromycin + Glyburide Major
- Fluconazole + Glyburide Major
- Glyburide + Insulin degludec-liraglutide Major
Frequently asked questions
Can I take Glyburide with Tongkat ali?
MediHelp rates the interaction as minor. Glyburide and Tongkat ali have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tongkat ali has been reported to have glucose-lowering effects in preclinical and limited human data. Combined with glyburide it could contribute to hypoglycemia.
How serious is the interaction between Glyburide and Tongkat ali?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal supplement use and monitor blood glucose. Adjust the glyburide dose if hypoglycemia occurs.
What other medicines interact with Glyburide?
MediHelp also lists interactions of Glyburide with, for example, Bosentan, Cholic acid, Ciprofloxacin. The full list is on the Glyburide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
