Drug interactions
Glyburide + Triamcinolone acetonide injectable
Severity: Moderate
Glyburide and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids raise blood glucose and can offset the effect of glyburide. Injected triamcinolone can produce hyperglycemia lasting days to weeks.
What this interaction means in plain words
Glyburide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroid-induced insulin resistance and increased hepatic gluconeogenesis oppose sulfonylurea action.
What to do
Monitor blood glucose for several days to weeks after injection and temporarily increase the glyburide dose or add therapy if needed. Watch for hypoglycemia as the steroid effect wears off.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Glyburide
- Bosentan + Glyburide Contraindicated
- Cholic acid + Glyburide Major
- Ciprofloxacin + Glyburide Major
- Clarithromycin + Glyburide Major
- Fluconazole + Glyburide Major
- Glyburide + Insulin degludec-liraglutide Major
Frequently asked questions
Can I take Glyburide with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Glyburide and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids raise blood glucose and can offset the effect of glyburide. Injected triamcinolone can produce hyperglycemia lasting days to weeks.
How serious is the interaction between Glyburide and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose for several days to weeks after injection and temporarily increase the glyburide dose or add therapy if needed. Watch for hypoglycemia as the steroid effect wears off.
What other medicines interact with Glyburide?
MediHelp also lists interactions of Glyburide with, for example, Bosentan, Cholic acid, Ciprofloxacin. The full list is on the Glyburide page.
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