Drug interactions
Glycopyrronium tosylate + Umeclidinium-vilanterol
Severity: Minor
Glycopyrronium tosylate and Umeclidinium-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both umeclidinium and glycopyrronium are antimuscarinics. Although the tosylate product is applied topically, some systemic absorption occurs, so additive anticholinergic effects such as dry mouth, urinary retention and blurred vision are possible.
What this interaction means in plain words
Glycopyrronium tosylate and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antimuscarinic pharmacodynamic effects.
What to do
Monitor for anticholinergic effects such as urinary retention, constipation and visual disturbance. Reduce use of other anticholinergics if symptoms occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Glycopyrronium tosylate and Umeclidinium-vilanterol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Umeclidinium-vilanterol
Frequently asked questions
Can I take Glycopyrronium tosylate with Umeclidinium-vilanterol?
MediHelp rates the interaction as minor. Glycopyrronium tosylate and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both umeclidinium and glycopyrronium are antimuscarinics. Although the tosylate product is applied topically, some systemic absorption occurs, so additive anticholinergic effects such as dry mouth, urinary retention and blurred vision are possible.
How serious is the interaction between Glycopyrronium tosylate and Umeclidinium-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects such as urinary retention, constipation and visual disturbance. Reduce use of other anticholinergics if symptoms occur.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
