Drug interactions
Gotu kola + Tolbutamide
Severity: Minor
Gotu kola and Tolbutamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Gotu kola has reported glucose-lowering activity in preclinical work, so combination with tolbutamide could theoretically increase hypoglycemia risk. No clinical reports confirm this.
What this interaction means in plain words
Gotu kola and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive blood glucose lowering; not established in humans.
What to do
Monitor blood glucose if gotu kola is taken regularly with tolbutamide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolbutamide
- Glyburide-metformin + Tolbutamide Major
- Insulin degludec-liraglutide + Tolbutamide Major
- Aceclofenac + Tolbutamide Moderate
- Acemetacin + Tolbutamide Moderate
- Acetylsalicylic acid + Tolbutamide Moderate
- Albiglutide + Tolbutamide Moderate
Frequently asked questions
Can I take Gotu kola with Tolbutamide?
MediHelp rates the interaction as minor. Gotu kola and Tolbutamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Gotu kola has reported glucose-lowering activity in preclinical work, so combination with tolbutamide could theoretically increase hypoglycemia risk. No clinical reports confirm this.
How serious is the interaction between Gotu kola and Tolbutamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if gotu kola is taken regularly with tolbutamide.
What other medicines interact with Tolbutamide?
MediHelp also lists interactions of Tolbutamide with, for example, Glyburide-metformin, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolbutamide page.
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