Drug interactions
Green tea + Procarbazine
Severity: Moderate
Green tea and Procarbazine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Procarbazine has monoamine oxidase inhibiting activity, and caffeine-containing products may provoke hypertensive reactions or arrhythmias. Large amounts of green tea could therefore increase cardiovascular risk.
What this interaction means in plain words
Green tea and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Green tea belongs to Gastrointestinal Tract; Procarbazine belongs to Oncology.
Why it happens
Procarbazine's MAO inhibition combined with caffeine's sympathomimetic effects may enhance pressor responses.
What to do
Advise patients to avoid excessive green tea and other caffeine-containing products during procarbazine therapy. Monitor blood pressure and report palpitations or severe headache.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Frequently asked questions
Can I take Green tea with Procarbazine?
MediHelp rates the interaction as moderate. Green tea and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine has monoamine oxidase inhibiting activity, and caffeine-containing products may provoke hypertensive reactions or arrhythmias. Large amounts of green tea could therefore increase cardiovascular risk.
How serious is the interaction between Green tea and Procarbazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid excessive green tea and other caffeine-containing products during procarbazine therapy. Monitor blood pressure and report palpitations or severe headache.
What other medicines interact with Green tea?
MediHelp also lists interactions of Green tea with, for example, Adenosine, Benzphetamine, Bortezomib. The full list is on the Green tea page.
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