Drug interactions
Green tea + Tranylcypromine
Severity: Moderate
Green tea and Tranylcypromine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Green tea contains caffeine and catechins. Caffeine in large amounts with an MAO inhibitor may provoke tachycardia, palpitations or hypertensive reactions, although typical beverage amounts carry a modest risk.
What this interaction means in plain words
Green tea and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Green tea belongs to Gastrointestinal Tract; Tranylcypromine belongs to Central Nervous System.
Why it happens
Caffeine's sympathomimetic action combined with MAO inhibition and increased catecholamine availability.
What to do
Advise limiting green tea and other caffeine sources, and avoid concentrated green tea extracts. Monitor blood pressure and heart rate if the patient reports palpitations or headache.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tranylcypromine
- 5-HTP + Tranylcypromine Contraindicated
- Amitriptyline + Tranylcypromine Contraindicated
- Amoxapine + Tranylcypromine Contraindicated
- Atomoxetine + Tranylcypromine Contraindicated
- Benzphetamine + Tranylcypromine Contraindicated
- Brimonidine + Tranylcypromine Contraindicated
Other interactions of Green tea
- Adenosine + Green tea Moderate
- Benzphetamine + Green tea Moderate
- Bortezomib + Green tea Moderate
- Dextroamphetamine + Green tea Moderate
- Diethylpropion + Green tea Moderate
- Ephedrine + Green tea Moderate
Frequently asked questions
Can I take Green tea with Tranylcypromine?
MediHelp rates the interaction as moderate. Green tea and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Green tea contains caffeine and catechins. Caffeine in large amounts with an MAO inhibitor may provoke tachycardia, palpitations or hypertensive reactions, although typical beverage amounts carry a modest risk.
How serious is the interaction between Green tea and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise limiting green tea and other caffeine sources, and avoid concentrated green tea extracts. Monitor blood pressure and heart rate if the patient reports palpitations or headache.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
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