Drug interactions
Griseofulvin + Triamcinolone
Severity: Minor
Griseofulvin and Triamcinolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Griseofulvin is a CYP3A4 inducer and may speed the metabolism of triamcinolone, potentially weakening its anti-inflammatory effect. The clinical significance is likely modest, particularly for local injections.
What this interaction means in plain words
Griseofulvin and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Griseofulvin belongs to Anti Fungals; Triamcinolone belongs to Endocrine.
Why it happens
Griseofulvin induces hepatic CYP3A4, increasing triamcinolone clearance.
What to do
Monitor for reduced clinical response to triamcinolone during griseofulvin therapy. Increase the steroid dose only if therapeutic effect is clearly inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Other interactions of Griseofulvin
Frequently asked questions
Can I take Griseofulvin with Triamcinolone?
MediHelp rates the interaction as minor. Griseofulvin and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Griseofulvin is a CYP3A4 inducer and may speed the metabolism of triamcinolone, potentially weakening its anti-inflammatory effect. The clinical significance is likely modest, particularly for local injections.
How serious is the interaction between Griseofulvin and Triamcinolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced clinical response to triamcinolone during griseofulvin therapy. Increase the steroid dose only if therapeutic effect is clearly inadequate.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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