Drug interactions
Henbane + Ipratropium-salbutamol
Severity: Moderate
Henbane and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine-type tropane alkaloids with antimuscarinic activity. Combined with ipratropium, it can add to anticholinergic effects, and henbane is also toxic with a narrow margin.
What this interaction means in plain words
Henbane and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive muscarinic antagonism from tropane alkaloids in henbane and ipratropium.
What to do
Advise the patient to avoid henbane preparations. If used, monitor for tachycardia, urinary retention, confusion and dry mouth.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Frequently asked questions
Can I take Henbane with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Henbane and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine-type tropane alkaloids with antimuscarinic activity. Combined with ipratropium, it can add to anticholinergic effects, and henbane is also toxic with a narrow margin.
How serious is the interaction between Henbane and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient to avoid henbane preparations. If used, monitor for tachycardia, urinary retention, confusion and dry mouth.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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