Drug interactions
Henbane + Pancuronium
Severity: Moderate
Henbane and Pancuronium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine, antimuscarinic alkaloids that add to pancuronium's vagolytic effect. This may increase the risk of tachycardia.
What this interaction means in plain words
Henbane and Pancuronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antimuscarinic effects on cardiac vagal tone.
What to do
Ask about herbal use before anesthesia and monitor heart rate and ECG if henbane has been taken.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pancuronium
Frequently asked questions
Can I take Henbane with Pancuronium?
MediHelp rates the interaction as moderate. Henbane and Pancuronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine, antimuscarinic alkaloids that add to pancuronium's vagolytic effect. This may increase the risk of tachycardia.
How serious is the interaction between Henbane and Pancuronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use before anesthesia and monitor heart rate and ECG if henbane has been taken.
What other medicines interact with Pancuronium?
MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Pancuronium page.
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