Drug interactions
Henbane + Quinidine
Severity: Moderate
Henbane and Quinidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains anticholinergic tropane alkaloids such as hyoscyamine and scopolamine. Quinidine also has anticholinergic and vagolytic effects, so combined use may cause additive anticholinergic effects such as tachycardia, dry mouth and confusion.
What this interaction means in plain words
Henbane and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive anticholinergic (antimuscarinic) effects.
What to do
Avoid the herbal product where possible. If used, monitor heart rate and anticholinergic symptoms.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Frequently asked questions
Can I take Henbane with Quinidine?
MediHelp rates the interaction as moderate. Henbane and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains anticholinergic tropane alkaloids such as hyoscyamine and scopolamine. Quinidine also has anticholinergic and vagolytic effects, so combined use may cause additive anticholinergic effects such as tachycardia, dry mouth and confusion.
How serious is the interaction between Henbane and Quinidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the herbal product where possible. If used, monitor heart rate and anticholinergic symptoms.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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