Drug interactions
Henbane + Rimantadine
Severity: Moderate
Henbane and Rimantadine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Henbane contains hyoscyamine and scopolamine, which are centrally active antimuscarinics that can cause confusion, hallucinations and delirium. With rimantadine, which can itself cause CNS effects, additive neuropsychiatric toxicity is possible, although direct data are lacking.
What this interaction means in plain words
Henbane and Rimantadine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central anticholinergic and CNS effects.
What to do
Avoid henbane in patients taking rimantadine where possible. If used, monitor for confusion, agitation, urinary retention and tachycardia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Rimantadine
Frequently asked questions
Can I take Henbane with Rimantadine?
MediHelp rates the interaction as moderate. Henbane and Rimantadine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Henbane contains hyoscyamine and scopolamine, which are centrally active antimuscarinics that can cause confusion, hallucinations and delirium. With rimantadine, which can itself cause CNS effects, additive neuropsychiatric toxicity is possible, although direct data are lacking.
How serious is the interaction between Henbane and Rimantadine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid henbane in patients taking rimantadine where possible. If used, monitor for confusion, agitation, urinary retention and tachycardia.
What other medicines interact with Rimantadine?
MediHelp also lists interactions of Rimantadine with, for example, Atropine iv /, Glycopyrrolate, Glycopyrronium. The full list is on the Rimantadine page.
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